The pituitary gland in the brain produces a “luteinising” hormone, also called lutropin, that induces the male testes to make testosterone, the primary androgen that controls and maintains masculine characteristics. Testosterone attached to prostate cancers causes the cells to multiply and grow. If a drug causes the pituitary to produce less lutropin, testosterone levels are reduced. This may cause the prostate cancer to shrink or develop more slowly.
Anti-androgen drugs block these testosterone receptors so they can’t instruct cancer cells to grow and multiply. Anti-androgens do not cure prostate cancer, but they can improve some of the disease’s symptoms and help the patient live longer.
The generic name for anti-androgen drug Eulexin is Flutamine. The anti-cancer drug Leuprolide is sometimes prescribed to accompany Euxelin. The two drugs should be taken together, exactly in the amount prescribed, without interruption.
Eulexin has caused some patients to suffer fatal liver failure. This is rare. Have your liver tested before taking Eulexin. If you experience liver problems, reduce your dosage or stop taking the drug. If you think you’re having liver problems, tell your doctor immediately. Look for itching, flu-like symptoms, yellowing skin or eyes, loss of appetite and tenderness on the upper right side of your abdomen.
Bicalutamide, also known by the brand name Casodex, is an oral medication that is used in the treatment of prostate cancer. It belongs to a group of drugs called non-steroidal antiandrogens, and it works by blocking male hormones. It’s always taken along with another drug, and the two work together to stop the spread and growth of cancer cells. Bicalutamide should only be taken under the supervision of a doctor and all dosage instructions should be followed carefully.
As a non-steroidal antiandrogen, bicalutamide works by blocking the action of androgens, or male hormones, such as testosterone. When used together with a luteinizing hormone-releasing hormone such as leuprolide, bicalutamide(CAS:90357-06-5) helps to stop the growth and spread of cancer cells. It does not destroy existing cancer cells, so it is not considered a cure. Even if a patient feels better, he or she should not discontinue use unless instructed by the doctor.
Some common milder side effects are dizziness, weakness, headaches, hot flashes, back pain, digestive issues, weight gain or loss, cold symptoms, swollen or painful breasts, loss of sexual desire, and increased urination at night. Liver damage is possible and blood should be tested and monitored to ensure the medication is working with minimum possible side effects.